Jeffrey A Toretsky : rechercher sur Z-Library

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1

Insulin-like growth factor type 1 (IGF–1) and IGF binding protein–3 in patients with Ewing sarcoma family of tumors

Jeffrey A. Toretsky, Seth M. Steinberg, Manjusha Thakar, Debra Counts, Baiba Pironis B.A., Carrie Parente B.A., Allen Eskenazi, Lee Helman, Leonard H. Wexler

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 101 KB

english, 2001

2

Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature

Brian P Brooks, Jeanne M Meck, Bassem R Haddad, Claude Bendavid, Delphine Blain, Jeffrey A Toretsky

Journal:

BMC Medical Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2006

3

Wnt/Frizzled signaling in Ewing sarcoma

Aykut Üren, Vladimir Wolf, Yu-Feng Sun, Amir Azari, Jeffrey S. Rubin, Jeffrey A. Toretsky

Journal:

Pediatric Blood & Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 243 KB

english, 2004

4

Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival

Kevin Chen, Shannon Fallen, Hatice Özel Abaan, Mutlu Hayran, Corina Gonzalez, Felasfa Wodajo, Tobey MacDonald, Jeffrey A. Toretsky, Aykut Üren

Journal:

Pediatric Blood & Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 427 KB

english, 2008

5

Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia

Margarita Raygada, Diane C. Arthur, Alan S. Wayne, Owen M. Rennert, Jeffrey A. Toretsky, Constantine A. Stratakis

Journal:

Pediatric Blood & Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 98 KB

english, 2010

6

PTPL1: a large phosphatase with a split personality

Ogan D. Abaan, Jeffrey A. Toretsky

Journal:

Cancer and Metastasis Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 233 KB

english, 2008

7

Hunting ALK to feed targeted cancer therapy

Wellstein, Anton, Toretsky, Jeffrey A

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 387 KB

english, 2011

8

Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells

Wang, Suna, Thakar, Manjusha, Smolinski, Kara N, Yin, Jing, Zou, Tong-Tong, Kong, Dehe, Abraham, John M, Toretsky, Jeffrey A, Meltzer, Stephen J, Souza, Rhonda F

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 188 KB

english, 1999

9

PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis

Abaan, Ogan D, Levenson, Amy, Khan, Osman, Furth, Priscilla A, Üren, Aykut, Toretsky, Jeffrey A

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 320 KB

english, 2005

10

Inhibition of EWS-FLI-1 fusion protein with antisense oligodeoxynucleotides

Jeffrey A. Toretsky, Yvette Connell, Len Neckers, Narayan K. Bhat

Journal:

Journal of Neuro-Oncology

Année:

1997

Langue:

english

Fichier:

PDF, 206 KB

english, 1997

11

Evaluation of arsenic trioxide by the pediatric preclinical testing program with a focus on Ewing sarcoma

Malcolm A. Smith, Min H. Kang, C. Patrick Reynolds, Raushan T. Kurmasheva, Denise Alexander, Catherine A. Billups, Jeffrey A. Toretsky, Peter J. Houghton

Journal:

Pediatric Blood & Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 68 KB

english, 2012

12

Expression of PAX3 in Ewing's Sarcoma Family of Tumors

Theodor W. Schulte, Jeffrey A. Toretsky, Elisabeth Ress, Lee Helman, Leonard M. Neckers

Journal:

Biochemical and Molecular Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 552 KB

english, 1997

13

PBK/TOPK Is a Novel Mitotic Kinase Which Is Upregulated in Burkitt's Lymphoma and Other Highly Proliferative Malignant Cells

Michelle Simons-Evelyn, Kim Bailey-Dell, Jeffrey A. Toretsky, Douglas D. Ross, Robert Fenton, Dhan Kalvakolanu, Aaron P. Rapoport

Journal:

Blood Cells, Molecules, and Diseases

Année:

2001

Langue:

english

Fichier:

PDF, 71 KB

english, 2001

14

Myoepithelioma metastatic to the orbit

Campbell Waldrop, Sajeev S. Kathuria, Jeffrey A. Toretsky, Chen-Chih J. Sun

Journal:

American Journal of Ophthalmology

Année:

2001

Langue:

english

Fichier:

PDF, 249 KB

english, 2001

15

IGF-1R targeted treatment of sarcoma

Jeffrey A Toretsky, Richard Gorlick

Journal:

The Lancet Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 106 KB

english, 2010

16

Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1

Abaan, Ogan D., Hendriks, Wiljan, Üren, Aykut, Toretsky, Jeffrey A., Erkizan, Hayriye V.

Journal:

Experimental Cell Research

Année:

2013

Langue:

english

Fichier:

PDF, 847 KB

english, 2013

17

Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma

Paige, Mikell, Kosturko, George, Bulut, Güllay, Miessau, Matthew, Rahim, Said, Toretsky, Jeffrey A., Brown, Milton L., Üren, Aykut

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.73 MB

english, 2014

18

OBITUARY

Paige, Mikell, Kosturko, George, Bulut, Güllay, Miessau, Matthew, Rahim, Said, Toretsky, Jeffrey A., Brown, Milton L., Üren, Aykut

Journal:

Année:

1937

Langue:

english

Fichier:

PDF, 353 KB

english, 1937

19

Mutant Conformation of p53 Translated in vitro or in vivo Requires Functional HSP90

Mikhail V. Blagosklonny, Jeffrey Toretsky, Sean Bohen and Len Neckers

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

20

Recombinant EWS-FLI1 Oncoprotein Activates Transcription †

Üren, Aykut, Tcherkasskaya, Olga, Toretsky, Jeffrey A.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 411 KB

english, 2004

21

Analysis of serum insulin growth factor-1 concentrations in localized osteosarcoma: A children's oncology group study

Borinstein, Scott C., Barkauskas, Donald A., Bernstein, Mark, Goorin, Allen, Gorlick, Richard, Krailo, Mark, Schwartz, Cindy L., Wexler, Leonard H., Toretsky, Jeffrey A.

Journal:

Pediatric Blood & Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 551 KB

english, 2014

22

Synthesis and Structure–Activity Relationship Studies of Small Molecule Disruptors of EWS-FLI1 Interactions in Ewing’s Sarcoma

Tosso, Perrer N., Kong, Yali, Scher, Lauren, Cummins, Ryan, Schneider, Jeffrey, Rahim, Said, Holman, K. Travis, Toretsky, Jeffrey, Wang, Kan, Üren, Aykut, Brown, Milton L.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 766 KB

english, 2014

23

Insulin-Like Growth Factor 1 Receptor as a Therapeutic Target in Ewing Sarcoma: Lack of Consistent Upregulation or Recurrent Mutation and a Review of the Clinical Trial Literature

O'Neill, Alison, Shah, Nilay, Zitomersky, Naamah, Ladanyi, Marc, Shukla, Neerav, Üren, Aykut, Loeb, David, Toretsky, Jeffrey

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1011 KB

english, 2013

24

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

Schlottmann, Silke, Erkizan, Hayriye V., Barber-Rotenberg, Julie S., Knights, Chad, Cheema, Amrita, Üren, Aykut, Avantaggiati, Maria L., Toretsky, Jeffrey A.

Journal:

Frontiers in Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2012

25

Ezrin binds to DEAD-box RNA helicase DDX3 and regulates its function and protein level

Çelik, Haydar, Sajwan, Kamal P., Selvanathan, Saravana P., Marsh, Ben J., Pai, Amrita V., Saygideger Kont, Yasemin, Han, Jenny, Minas, Tsion Z., Rahim, Said, Erkizan, Hayriye Verda, Toretsky, Jeffrey

Journal:

Molecular and Cellular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 3.30 MB

english, 2015

26

Synovial sarcoma is a gateway to the role of chromatin remodeling in cancer

Zöllner, Stefan K., Rössig, Claudia, Toretsky, Jeffrey A.

Journal:

Cancer and Metastasis Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2015

27

Ewing's sarcoma oncoprotein EWS–FLI1: the perfect target without a therapeutic agent

Üren, Aykut, Toretsky, Jeffrey A

Journal:

Future Oncology

Année:

2005

Langue:

english

Fichier:

PDF, 348 KB

english, 2005

28

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors

Erkizan, Hayriye V., Scher, Lauren J., Gamble, S. Ellen, Barber-Rotenberg, Julie S., Sajwan, Kamal P., Üren, Aykut, Toretsky, Jeffrey A.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 9.13 MB

english, 2011

29

VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells

Ringer, Lymor, Sirajuddin, Paul, Heckler, Mary, Ghosh, Anup, Suprynowicz, Frank, Yenugonda, Venkata M., Brown, Milton L., Toretsky, Jeffrey A., Üren, Aykut, Lee, YiChien, MacDonald, Tobey J., Rodrigue

Journal:

Cancer Biology & Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2011

30

Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non–Small Cell Lung Cancer Cells

Saygideğer-Kont, Yasemin, Minas, Tsion Zewdu, Jones, Hayden, Hour, Sarah, Çelik, Haydar, Temel, Idil, Han, Jenny, Atabey, Nese, Erkizan, Hayriye Verda, Toretsky, Jeffrey A., Üren, Aykut

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2016

31

Tumor Expression of 4-1BB Ligand Sustains Tumor Lytic T Cells

Zhang, Hua, Merchant, Melinda S., Chua, Kevin S., Khanna, Chand, Helman, Lee J., Telford, Bill, Ward, Yvona, Summers, Jeffrey, Toretsky, Jeffrey A., Thomas, Elaine K., June, Carl H., Mackall, Crystal

Journal:

Cancer Biology & Therapy

Année:

2003

Langue:

english

Fichier:

PDF, 379 KB

english, 2003

32

Novel Translocation in Acute Megakaryoblastic Leukemia (AML-M7)

Toretsky, Jeffrey A., Everly, Eileen M., Padilla-Nash, Hesed M., Chen, Allen, Abruzzo, Lynne V., Eskenazi, Allen E., Frantz, Chris, Ried, Thomas, Stamberg, Judith

Journal:

Journal of Pediatric Hematology/Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 685 KB

english, 2003

33

10.1097/00000421-200306000-00019

Toretsky, Jeffrey, Jenson, James, Sun, Chen-Chih, Eskenazi, Allen, Campbell, Andrew, Hunger, Stephen, Caires, Aimee, Frantz, Christopher, Hill, J, Stamberg, Judith

Journal:

American Journal of Clinical Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 921 KB

english, 2003

34

Glypican-3 Expression in Wilms Tumor and Hepatoblastoma

Toretsky, Jeffrey A., Zitomersky, Naamah L., Eskenazi, Allen E., Voigt, Roger W., Strauch, Eric D., Sun, Chem Chih, Huber, Reed, Meltzer, Steven J., Schlessinger, David

Journal:

Journal of Pediatric Hematology/Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 622 KB

english, 2001

35

Translocation (11;15;19): a Highly Specific Chromosome Rearrangement Associated With Poorly Differentiated Thymic Carcinoma in Young Patients

Toretsky, Jeffrey A., Jenson, James, Sun, Chen-Chih, Eskenazi, Allen E., Campbell, Andrew, Hunger, Stephen P., Caires, Aimee, Frantz, Christopher, Hill, J Laurance, Stamberg, Judith

Journal:

American Journal of Clinical Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 921 KB

english, 2003

36

Cytogenetics and experimental models

Toretsky, Jeffrey A., Helman, Lee J.

Journal:

Current Opinion in Oncology

Année:

1997

Fichier:

PDF, 4.25 MB

1997

37

#511 Insulin-like Growth Factor-I Receptor is Necessary for EWS/FLI-1 Induced Transformation of Fibroblasts

Toretsky, J. A., Kalebic, T., Blakesley, V., LeRoith, D., Helman, L., Moscow, Jeffrey

Journal:

Journal of Pediatric Hematology/Oncology

Année:

1996

Fichier:

PDF, 89 KB

1996

38

Cerebral edema and priapism in an adolescent with acute lymphoblastic leukemia

CHOO-KANG, LEE R., JONES, DIANNE M., FEHR, JAMES J., ESKENAZI, ALLEN E., TORETSKY, JEFFREY A.

Journal:

Pediatric Emergency Care

Année:

1999

Fichier:

PDF, 283 KB

1999

39

Pediatric malignancies provide unique cancer therapy targets

??ren, Aykut, Toretsky, Jeffrey A

Journal:

Current Opinion in Pediatrics

Année:

2005

Langue:

english

Fichier:

PDF, 86 KB

english, 2005

40

A probable primary malignant bone tumor in a pre-Columbian human humerus from Cerro Brujo, Bocas del Toro, Panamá

Smith-Guzmán, Nicole E., Toretsky, Jeffrey A., Tsai, Jason, Cooke, Richard G.

Journal:

International Journal of Paleopathology

Année:

2017

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2017

41

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

Awad, Ola, Yustein, Jason T., Shah, Preeti, Gul, Naheed, Katuri, Varalakshmi, O'Neill, Alison, Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Loeb, David M., Lee, Terence

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 3.99 MB

english, 2010

42

Beta-Catenin Accelerates Human Papilloma Virus Type-16 Mediated Cervical Carcinogenesis in Transgenic Mice

Bulut, Gülay, Fallen, Shannon, Beauchamp, Elspeth M., Drebing, Lauren E., Sun, Junfeng, Berry, Deborah L., Kallakury, Bhaskar, Crum, Christopher P., Toretsky, Jeffrey A., Schlegel, Richard, Üren, Ayku

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2011

43

An Intrinsically Disordered Region of the Acetyltransferase p300 with Similarity to Prion-Like Domains Plays a Role in Aggregation

Kirilyuk, Alexander, Shimoji, Mika, Catania, Jason, Sahu, Geetaram, Pattabiraman, Nagarajan, Giordano, Antonio, Albanese, Christopher, Mocchetti, Italo, Toretsky, Jeffrey A., Uversky, Vladimir N., Ava

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2012

44

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation

Glover, Jason, Man, Tsz-Kwong, Barkauskas, Donald A., Hall, David, Tello, Tanya, Sullivan, Mary Beth, Gorlick, Richard, Janeway, Katherine, Grier, Holcombe, Lau, Ching, Toretsky, Jeffrey A., Borinstei

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2017

45

Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis

Ma, Yan, Baltezor, Michael, Rajewski, Lian, Crow, Jennifer, Samuel, Glenson, Staggs, Vincent S., Chastain, Katherine M., Toretsky, Jeffrey A., Weir, Scott J., Godwin, Andrew K.

Journal:

Journal of Molecular Medicine

Année:

2019

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2019

46

Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis

Ma, Yan, Baltezor, Michael, Rajewski, Lian, Crow, Jennifer, Samuel, Glenson, Staggs, Vincent S., Chastain, Katherine M., Toretsky, Jeffrey A., Weir, Scott J., Godwin, Andrew K.

Journal:

Journal of Molecular Medicine

Année:

2019

Fichier:

PDF, 3.17 MB

2019

47

A novel PARD3B-NUTM1 fusion in an aggressive primary CNS embryonal tumor in a young adult

Ko, Kyungmin, Kitani, Takashi, Harris, Brent T., Anaizi, Amjad N., Solomon, David, Perry, Arie, Toretsky, Jeffrey, Ozdemirli, Metin

Journal:

Acta Neuropathologica Communications

Année:

2020

Fichier:

PDF, 1.25 MB

2020